세로토닌 신호 억제를 통한 당뇨병 및 지방간 억제 효과 규명

출처 : 한국과학기술원
등록일 : 2021-10-08
조회 : 83

<div style="text-align: justify;" align="justify"> </div><div style="text-align: center;" align="center"><a href="https://news.kaist.ac.kr/news/html/news/?mode=V&mng_no=16391&skey=category&sval=%EC%97%B0%EA%B5%AC&list_s_date=&list_e_date=&GotoPage=1" target="_blank"><img src="https://news.kaist.ac.kr/_prog/download/?editor_image=/images/000038/photo1.jpg_15.jpg" title="(왼쪽부터) 의과학대학원 김하일 교수, 최원근 박사" alt="(왼쪽부터) 의과학대학원 김하일 교수, 최원근 박사" style="color: rgb(102, 102, 102); font-family: "Noto Sans CJK KR", "Noto Sans KR", "Noto Sans EOT", SimHei, sans-serif, 맑은고딕, "Malgun Gothic", -apple-system, BlinkMacSystemFont, "Segoe UI", Roboto, "Helvetica Neue", Arial, sans-serif, FangSong, 仿宋, STFangSong, 华文仿宋, "Apple Color Emoji", "Segoe UI Emoji", "Segoe UI Symbol", AppleGothic, Dotum, arial, sans-serif; font-size: inherit; letter-spacing: -0.02em; text-align: center; box-sizing: border-box; margin: 0px; padding: 0px; -webkit-font-smoothing: antialiased; -webkit-print-color-adjust: exact; border: 0px solid rgb(0, 0, 0); font-style: inherit; font-variant: inherit; font-weight: inherit; font-stretch: inherit; line-height: inherit; vertical-align: middle; -webkit-tap-highlight-color: transparent; max-width: 100%; width: 369px; height: 237px;"></a></div><p style="text-align: justify; box-sizing: border-box; margin-top: 20px; margin-bottom: 20px; -webkit-font-smoothing: antialiased; -webkit-print-color-adjust: exact; border: 0px; font-variant-numeric: inherit; font-variant-east-asian: inherit; font-stretch: inherit; font-size: 16px; line-height: 24px; vertical-align: baseline; font-family: "Noto Sans CJK KR", "Noto Sans KR", "Noto Sans EOT", SimHei, sans-serif, 맑은고딕, "Malgun Gothic", -apple-system, BlinkMacSystemFont, "Segoe UI", Roboto, "Helvetica Neue", Arial, sans-serif, FangSong, 仿宋, STFangSong, 华文仿宋, "Apple Color Emoji", "Segoe UI Emoji", "Segoe UI Symbol", AppleGothic, Dotum, arial, sans-serif; letter-spacing: -0.02em; overflow-wrap: break-word; color: rgb(102, 102, 102);" align="justify">< (왼쪽부터) 의과학대학원 김하일 교수, 최원근 박사 ><p style="box-sizing: border-box; margin-top: 20px; margin-bottom: 20px; -webkit-font-smoothing: antialiased; -webkit-print-color-adjust: exact; border: 0px; font-variant-numeric: inherit; font-variant-east-asian: inherit; font-stretch: inherit; font-size: 16px; line-height: 24px; vertical-align: baseline; font-family: "Noto Sans CJK KR", "Noto Sans KR", "Noto Sans EOT", SimHei, sans-serif, 맑은고딕, "Malgun Gothic", -apple-system, BlinkMacSystemFont, "Segoe UI", Roboto, "Helvetica Neue", Arial, sans-serif, FangSong, 仿宋, STFangSong, 华文仿宋, "Apple Color Emoji", "Segoe UI Emoji", "Segoe UI Symbol", AppleGothic, Dotum, arial, sans-serif; letter-spacing: -0.02em; overflow-wrap: break-word; color: rgb(102, 102, 102);">&nbsp;<p class="0" style="box-sizing: border-box; margin-top: 20px; margin-bottom: 20px; -webkit-font-smoothing: antialiased; -webkit-print-color-adjust: exact; border: 0px; font-variant-numeric: inherit; font-variant-east-asian: inherit; font-stretch: inherit; font-size: 16px; line-height: 24px; vertical-align: baseline; font-family: "Noto Sans CJK KR", "Noto Sans KR", "Noto Sans EOT", SimHei, sans-serif, 맑은고딕, "Malgun Gothic", -apple-system, BlinkMacSystemFont, "Segoe UI", Roboto, "Helvetica Neue", Arial, sans-serif, FangSong, 仿宋, STFangSong, 华文仿宋, "Apple Color Emoji", "Segoe UI Emoji", "Segoe UI Symbol", AppleGothic, Dotum, arial, sans-serif; letter-spacing: -0.02em; overflow-wrap: break-word; color: rgb(102, 102, 102); text-align: justify;" align="justify"><span style="box-sizing: border-box; margin: 0px; padding: 0px; -webkit-font-smoothing: antialiased; -webkit-print-color-adjust: exact; border: 0px; font-style: inherit; font-variant: inherit; font-weight: inherit; font-stretch: inherit; font-size: 11pt; line-height: 1.6; vertical-align: baseline; font-family: 돋움, dotum; letter-spacing: -0.02em; color: rgb(0, 0, 0);">우리 대학 의과학대학원 김하일 교수 연구팀이 분당서울대병원 내분비대사내과 최성희 교수 연구팀과 공동연구를 통해 지방조직의&nbsp;<span style="box-sizing: border-box; margin: 0px; padding: 0px; -webkit-font-smoothing: antialiased; -webkit-print-color-adjust: exact; border: 0px; font-style: inherit; font-variant: inherit; font-weight: inherit; font-stretch: inherit; font-size: 11pt; line-height: 1.6; vertical-align: baseline; font-family: 돋움, dotum; letter-spacing: 0pt; color: rgb(0, 0, 0);">*<span style="box-sizing: border-box; margin: 0px; padding: 0px; -webkit-font-smoothing: antialiased; -webkit-print-color-adjust: exact; border: 0px; font-style: inherit; font-variant: inherit; font-weight: inherit; font-stretch: inherit; font-size: 11pt; line-height: 1.6; vertical-align: baseline; font-family: 돋움, dotum; letter-spacing: -0.02em; color: rgb(0, 0, 0);">세로토닌<span style="box-sizing: border-box; margin: 0px; padding: 0px; -webkit-font-smoothing: antialiased; -webkit-print-color-adjust: exact; border: 0px; font-style: inherit; font-variant: inherit; font-weight: inherit; font-stretch: inherit; font-size: 11pt; line-height: 1.6; vertical-align: baseline; font-family: 돋움, dotum; letter-spacing: -0.02em; color: rgb(0, 0, 0);">&nbsp;<span style="box-sizing: border-box; margin: 0px; padding: 0px; -webkit-font-smoothing: antialiased; -webkit-print-color-adjust: exact; border: 0px; font-style: inherit; font-variant: inherit; font-weight: inherit; font-stretch: inherit; font-size: 11pt; line-height: 1.6; vertical-align: baseline; font-family: 돋움, dotum; letter-spacing: -0.02em; color: rgb(0, 0, 0);">신호 억제로 당뇨병 개선 및 지방간 억제 효과를 규명했다고&nbsp;<span style="box-sizing: border-box; margin: 0px; padding: 0px; -webkit-font-smoothing: antialiased; -webkit-print-color-adjust: exact; border: 0px; font-style: inherit; font-variant: inherit; font-weight: inherit; font-stretch: inherit; font-size: 11pt; line-height: 1.6; vertical-align: baseline; font-family: 돋움, dotum; letter-spacing: 0pt; color: rgb(0, 0, 0);">8<span style="box-sizing: border-box; margin: 0px; padding: 0px; -webkit-font-smoothing: antialiased; -webkit-print-color-adjust: exact; border: 0px; font-style: inherit; font-variant: inherit; font-weight: inherit; font-stretch: inherit; font-size: 11pt; line-height: 1.6; vertical-align: baseline; font-family: 돋움, dotum; letter-spacing: -0.02em; color: rgb(0, 0, 0);">일<span style="box-sizing: border-box; margin: 0px; padding: 0px; -webkit-font-smoothing: antialiased; -webkit-print-color-adjust: exact; border: 0px; font-style: inherit; font-variant: inherit; font-weight: inherit; font-stretch: inherit; font-size: 11pt; line-height: 1.6; vertical-align: baseline; font-family: 돋움, dotum; letter-spacing: -0.02em; color: rgb(0, 0, 0);">&nbsp;<span style="box-sizing: border-box; margin: 0px; padding: 0px; -webkit-font-smoothing: antialiased; -webkit-print-color-adjust: exact; border: 0px; font-style: inherit; font-variant: inherit; font-weight: inherit; font-stretch: inherit; font-size: 11pt; line-height: 1.6; vertical-align: baseline; font-family: 돋움, dotum; letter-spacing: -0.02em; color: rgb(0, 0, 0);">밝혔다<span style="box-sizing: border-box; margin: 0px; padding: 0px; -webkit-font-smoothing: antialiased; -webkit-print-color-adjust: exact; border: 0px; font-style: inherit; font-variant: inherit; font-weight: inherit; font-stretch: inherit; font-size: 11pt; line-height: 1.6; vertical-align: baseline; font-family: 돋움, dotum; letter-spacing: 0pt; color: rgb(0, 0, 0);">.<p class="0" style="box-sizing: border-box; margin-top: 20px; margin-bottom: 20px; -webkit-font-smoothing: antialiased; -webkit-print-color-adjust: exact; border: 0px; font-variant-numeric: inherit; font-variant-east-asian: inherit; font-stretch: inherit; font-size: 16px; line-height: 24px; vertical-align: baseline; font-family: "Noto Sans CJK KR", "Noto Sans KR", "Noto Sans EOT", SimHei, sans-serif, 맑은고딕, "Malgun Gothic", -apple-system, BlinkMacSystemFont, "Segoe UI", Roboto, "Helvetica Neue", Arial, sans-serif, FangSong, 仿宋, STFangSong, 华文仿宋, "Apple Color Emoji", "Segoe UI Emoji", "Segoe UI Symbol", AppleGothic, Dotum, arial, sans-serif; letter-spacing: -0.02em; overflow-wrap: break-word; color: rgb(102, 102, 102); text-align: justify;" align="justify"><span style="box-sizing: border-box; margin: 0px; padding: 0px; -webkit-font-smoothing: antialiased; -webkit-print-color-adjust: exact; border: 0px; font-style: inherit; font-variant: inherit; font-weight: inherit; font-stretch: inherit; font-size: 12pt; line-height: 1.6; vertical-align: baseline; font-family: "맑은 고딕"; letter-spacing: -0.02em;"><span style="box-sizing: border-box; margin: 0px; padding: 0px; -webkit-font-smoothing: antialiased; -webkit-print-color-adjust: exact; border: 0px; font-style: inherit; font-variant: inherit; font-weight: inherit; font-stretch: inherit; font-size: 11pt; line-height: 1.6; vertical-align: baseline; font-family: 돋움, dotum; letter-spacing: 0pt; color: rgb(0, 0, 0);">☞&nbsp;<span style="box-sizing: border-box; margin: 0px; padding: 0px; -webkit-font-smoothing: antialiased; -webkit-print-color-adjust: exact; border: 0px; font-style: inherit; font-variant: inherit; font-weight: inherit; font-stretch: inherit; font-size: 11pt; line-height: 1.6; vertical-align: baseline; font-family: 돋움, dotum; letter-spacing: -0.02em; color: rgb(0, 0, 0);">세로토닌&nbsp;<span style="box-sizing: border-box; margin: 0px; padding: 0px; -webkit-font-smoothing: antialiased; -webkit-print-color-adjust: exact; border: 0px; font-style: inherit; font-variant: inherit; font-weight: inherit; font-stretch: inherit; font-size: 11pt; line-height: 1.6; vertical-align: baseline; font-family: 돋움, dotum; letter-spacing: 0pt; color: rgb(0, 0, 0);">:&nbsp;<span style="box-sizing: border-box; margin: 0px; padding: 0px; -webkit-font-smoothing: antialiased; -webkit-print-color-adjust: exact; border: 0px; font-style: inherit; font-variant: inherit; font-weight: inherit; font-stretch: inherit; font-size: 11pt; line-height: 1.6; vertical-align: baseline; font-family: 돋움, dotum; letter-spacing: -0.02em; color: rgb(0, 0, 0);">신경전달물질 중 하나로 감정<span style="box-sizing: border-box; margin: 0px; padding: 0px; -webkit-font-smoothing: antialiased; -webkit-print-color-adjust: exact; border: 0px; font-style: inherit; font-variant: inherit; font-weight: inherit; font-stretch: inherit; font-size: 11pt; line-height: 1.6; vertical-align: baseline; font-family: 돋움, dotum; letter-spacing: 0pt; color: rgb(0, 0, 0);">,&nbsp;<span style="box-sizing: border-box; margin: 0px; padding: 0px; -webkit-font-smoothing: antialiased; -webkit-print-color-adjust: exact; border: 0px; font-style: inherit; font-variant: inherit; font-weight: inherit; font-stretch: inherit; font-size: 11pt; line-height: 1.6; vertical-align: baseline; font-family: 돋움, dotum; letter-spacing: -0.02em; color: rgb(0, 0, 0);">수면 등의 조절에 관여를 한다<span style="box-sizing: border-box; margin: 0px; padding: 0px; -webkit-font-smoothing: antialiased; -webkit-print-color-adjust: exact; border: 0px; font-style: inherit; font-variant: inherit; font-weight: inherit; font-stretch: inherit; font-size: 11pt; line-height: 1.6; vertical-align: baseline; font-family: 돋움, dotum; letter-spacing: 0pt; color: rgb(0, 0, 0);">.&nbsp;<span style="box-sizing: border-box; margin: 0px; padding: 0px; -webkit-font-smoothing: antialiased; -webkit-print-color-adjust: exact; border: 0px; font-style: inherit; font-variant: inherit; font-weight: inherit; font-stretch: inherit; font-size: 11pt; line-height: 1.6; vertical-align: baseline; font-family: 돋움, dotum; letter-spacing: -0.02em; color: rgb(0, 0, 0);">주로 위장관<span style="box-sizing: border-box; margin: 0px; padding: 0px; -webkit-font-smoothing: antialiased; -webkit-print-color-adjust: exact; border: 0px; font-style: inherit; font-variant: inherit; font-weight: inherit; font-stretch: inherit; font-size: 11pt; line-height: 1.6; vertical-align: baseline; font-family: 돋움, dotum; letter-spacing: 0pt; color: rgb(0, 0, 0);">,&nbsp;<span style="box-sizing: border-box; margin: 0px; padding: 0px; -webkit-font-smoothing: antialiased; -webkit-print-color-adjust: exact; border: 0px; font-style: inherit; font-variant: inherit; font-weight: inherit; font-stretch: inherit; font-size: 11pt; line-height: 1.6; vertical-align: baseline; font-family: 돋움, dotum; letter-spacing: -0.02em; color: rgb(0, 0, 0);">혈소판<span style="box-sizing: border-box; margin: 0px; padding: 0px; -webkit-font-smoothing: antialiased; -webkit-print-color-adjust: exact; border: 0px; font-style: inherit; font-variant: inherit; font-weight: inherit; font-stretch: inherit; font-size: 11pt; line-height: 1.6; vertical-align: baseline; font-family: 돋움, dotum; letter-spacing: 0pt; color: rgb(0, 0, 0);">,&nbsp;<span style="box-sizing: border-box; margin: 0px; padding: 0px; -webkit-font-smoothing: antialiased; -webkit-print-color-adjust: exact; border: 0px; font-style: inherit; font-variant: inherit; font-weight: inherit; font-stretch: inherit; font-size: 11pt; line-height: 1.6; vertical-align: baseline; font-family: 돋움, dotum; letter-spacing: -0.02em; color: rgb(0, 0, 0);">뇌<span style="box-sizing: border-box; margin: 0px; padding: 0px; -webkit-font-smoothing: antialiased; -webkit-print-color-adjust: exact; border: 0px; font-style: inherit; font-variant: inherit; font-weight: inherit; font-stretch: inherit; font-size: 11pt; line-height: 1.6; vertical-align: baseline; font-family: 돋움, dotum; letter-spacing: 0pt; color: rgb(0, 0, 0);">,&nbsp;<span style="box-sizing: border-box; margin: 0px; padding: 0px; -webkit-font-smoothing: antialiased; -webkit-print-color-adjust: exact; border: 0px; font-style: inherit; font-variant: inherit; font-weight: inherit; font-stretch: inherit; font-size: 11pt; line-height: 1.6; vertical-align: baseline; font-family: 돋움, dotum; letter-spacing: -0.02em; color: rgb(0, 0, 0);">중추신경계에서 볼 수 있으며 행복을 느끼는 데에 기여한다고 여겨진다<span style="box-sizing: border-box; margin: 0px; padding: 0px; -webkit-font-smoothing: antialiased; -webkit-print-color-adjust: exact; border: 0px; font-style: inherit; font-variant: inherit; font-weight: inherit; font-stretch: inherit; font-size: 11pt; line-height: 1.6; vertical-align: baseline; font-family: 돋움, dotum; letter-spacing: 0pt; color: rgb(0, 0, 0);">.<p class="0" style="box-sizing: border-box; margin-top: 20px; margin-bottom: 20px; -webkit-font-smoothing: antialiased; -webkit-print-color-adjust: exact; border: 0px; font-variant-numeric: inherit; font-variant-east-asian: inherit; font-stretch: inherit; font-size: 14pt; line-height: 28px; vertical-align: baseline; font-family: "Noto Sans CJK KR", "Noto Sans KR", "Noto Sans EOT", SimHei, sans-serif, 맑은고딕, "Malgun Gothic", -apple-system, BlinkMacSystemFont, "Segoe UI", Roboto, "Helvetica Neue", Arial, sans-serif, FangSong, 仿宋, STFangSong, 华文仿宋, "Apple Color Emoji", "Segoe UI Emoji", "Segoe UI Symbol", AppleGothic, Dotum, arial, sans-serif; letter-spacing: -0.02em; overflow-wrap: break-word; color: rgb(102, 102, 102); text-align: justify;" align="justify"><span style="box-sizing: border-box; margin: 0px; padding: 0px; -webkit-font-smoothing: antialiased; -webkit-print-color-adjust: exact; border: 0px; font-style: inherit; font-variant: inherit; font-weight: inherit; font-stretch: inherit; font-size: 11pt; line-height: 1.6; vertical-align: baseline; font-family: 돋움, dotum; letter-spacing: -0.02em; color: rgb(0, 0, 0);">공동연구팀은 지방조직의 세로토닌 수용체&nbsp;<span style="box-sizing: border-box; margin: 0px; padding: 0px; -webkit-font-smoothing: antialiased; -webkit-print-color-adjust: exact; border: 0px; font-style: inherit; font-variant: inherit; font-weight: inherit; font-stretch: inherit; font-size: 11pt; line-height: 1.6; vertical-align: baseline; font-family: 돋움, dotum; letter-spacing: 0pt; color: rgb(0, 0, 0);">2B&nbsp;<span style="box-sizing: border-box; margin: 0px; padding: 0px; -webkit-font-smoothing: antialiased; -webkit-print-color-adjust: exact; border: 0px; font-style: inherit; font-variant: inherit; font-weight: inherit; font-stretch: inherit; font-size: 11pt; line-height: 1.6; vertical-align: baseline; font-family: 돋움, dotum; letter-spacing: -0.02em; color: rgb(0, 0, 0);">신호전달 억제를 통해 지방조직에서 분비되는 지방산을 조절하고 그 결과 혈중 지방산 수치를 낮추어 전신적인 대사 지표와 지방간을 개선하는 기작을 통해 지방간 치료제 연구 분야에 새로운 방향성을 제시하고 기존 대사질환 치료제 연구의 한계를 극복할 가능성을 제시해 주었다<span style="box-sizing: border-box; margin: 0px; padding: 0px; -webkit-font-smoothing: antialiased; -webkit-print-color-adjust: exact; border: 0px; font-style: inherit; font-variant: inherit; font-weight: inherit; font-stretch: inherit; font-size: 11pt; line-height: 1.6; vertical-align: baseline; font-family: 돋움, dotum; letter-spacing: 0pt; color: rgb(0, 0, 0);">.<span style="box-sizing: border-box; margin: 0px; padding: 0px; -webkit-font-smoothing: antialiased; -webkit-print-color-adjust: exact; border: 0px; font-style: inherit; font-variant: inherit; font-weight: inherit; font-stretch: inherit; font-size: 11pt; line-height: 1.6; vertical-align: baseline; font-family: 돋움, dotum; letter-spacing: -0.02em; color: rgb(0, 0, 0);">&nbsp;<p class="0" style="box-sizing: border-box; margin-top: 20px; margin-bottom: 20px; -webkit-font-smoothing: antialiased; -webkit-print-color-adjust: exact; border: 0px; font-variant-numeric: inherit; font-variant-east-asian: inherit; font-stretch: inherit; font-size: 16px; line-height: 24px; vertical-align: baseline; font-family: "Noto Sans CJK KR", "Noto Sans KR", "Noto Sans EOT", SimHei, sans-serif, 맑은고딕, "Malgun Gothic", -apple-system, BlinkMacSystemFont, "Segoe UI", Roboto, "Helvetica Neue", Arial, sans-serif, FangSong, 仿宋, STFangSong, 华文仿宋, "Apple Color Emoji", "Segoe UI Emoji", "Segoe UI Symbol", AppleGothic, Dotum, arial, sans-serif; letter-spacing: -0.02em; overflow-wrap: break-word; color: rgb(102, 102, 102); text-align: justify;" align="justify"><span style="box-sizing: border-box; margin: 0px; padding: 0px; -webkit-font-smoothing: antialiased; -webkit-print-color-adjust: exact; border: 0px; font-style: inherit; font-variant: inherit; font-weight: inherit; font-stretch: inherit; font-size: 11pt; line-height: 1.6; vertical-align: baseline; font-family: 돋움, dotum; letter-spacing: 0pt; color: rgb(0, 0, 0);">우리 대학&nbsp;<span style="box-sizing: border-box; margin: 0px; padding: 0px; -webkit-font-smoothing: antialiased; -webkit-print-color-adjust: exact; border: 0px; font-style: inherit; font-variant: inherit; font-weight: inherit; font-stretch: inherit; font-size: 11pt; line-height: 1.6; vertical-align: baseline; font-family: 돋움, dotum; letter-spacing: -0.02em; color: rgb(0, 0, 0);">의과학대학원 최원근 박사<span style="box-sizing: border-box; margin: 0px; padding: 0px; -webkit-font-smoothing: antialiased; -webkit-print-color-adjust: exact; border: 0px; font-style: inherit; font-variant: inherit; font-weight: inherit; font-stretch: inherit; font-size: 11pt; line-height: 1.6; vertical-align: baseline; font-family: 돋움, dotum; letter-spacing: 0pt; color: rgb(0, 0, 0);">,&nbsp;<span style="box-sizing: border-box; margin: 0px; padding: 0px; -webkit-font-smoothing: antialiased; -webkit-print-color-adjust: exact; border: 0px; font-style: inherit; font-variant: inherit; font-weight: inherit; font-stretch: inherit; font-size: 11pt; line-height: 1.6; vertical-align: baseline; font-family: 돋움, dotum; letter-spacing: -0.02em; color: rgb(0, 0, 0);">최원석 박사&nbsp;<span style="box-sizing: border-box; margin: 0px; padding: 0px; -webkit-font-smoothing: antialiased; -webkit-print-color-adjust: exact; border: 0px; font-style: inherit; font-variant: inherit; font-weight: inherit; font-stretch: inherit; font-size: 11pt; line-height: 1.6; vertical-align: baseline; font-family: 돋움, dotum; letter-spacing: 0pt; color: rgb(0, 0, 0);">(<span style="box-sizing: border-box; margin: 0px; padding: 0px; -webkit-font-smoothing: antialiased; -webkit-print-color-adjust: exact; border: 0px; font-style: inherit; font-variant: inherit; font-weight: inherit; font-stretch: inherit; font-size: 11pt; line-height: 1.6; vertical-align: baseline; font-family: 돋움, dotum; letter-spacing: -0.02em; color: rgb(0, 0, 0);">현 화순전남대학교병원 내분비대사내과<span style="box-sizing: border-box; margin: 0px; padding: 0px; -webkit-font-smoothing: antialiased; -webkit-print-color-adjust: exact; border: 0px; font-style: inherit; font-variant: inherit; font-weight: inherit; font-stretch: inherit; font-size: 11pt; line-height: 1.6; vertical-align: baseline; font-family: 돋움, dotum; letter-spacing: 0pt; color: rgb(0, 0, 0);">),&nbsp;<span style="box-sizing: border-box; margin: 0px; padding: 0px; -webkit-font-smoothing: antialiased; -webkit-print-color-adjust: exact; border: 0px; font-style: inherit; font-variant: inherit; font-weight: inherit; font-stretch: inherit; font-size: 11pt; line-height: 1.6; vertical-align: baseline; font-family: 돋움, dotum; letter-spacing: -0.02em; color: rgb(0, 0, 0);">분당서울대병원 내분비대사내과 오태정 교수가 공동 제<span style="box-sizing: border-box; margin: 0px; padding: 0px; -webkit-font-smoothing: antialiased; -webkit-print-color-adjust: exact; border: 0px; font-style: inherit; font-variant: inherit; font-weight: inherit; font-stretch: inherit; font-size: 11pt; line-height: 1.6; vertical-align: baseline; font-family: 돋움, dotum; letter-spacing: 0pt; color: rgb(0, 0, 0);">1&nbsp;<span style="box-sizing: border-box; margin: 0px; padding: 0px; -webkit-font-smoothing: antialiased; -webkit-print-color-adjust: exact; border: 0px; font-style: inherit; font-variant: inherit; font-weight: inherit; font-stretch: inherit; font-size: 11pt; line-height: 1.6; vertical-align: baseline; font-family: 돋움, dotum; letter-spacing: -0.02em; color: rgb(0, 0, 0);">저자로 참여한 이번 연구는 국제 학술지&nbsp;<span style="box-sizing: border-box; margin: 0px; padding: 0px; -webkit-font-smoothing: antialiased; -webkit-print-color-adjust: exact; border: 0px; font-style: inherit; font-variant: inherit; font-weight: inherit; font-stretch: inherit; font-size: 11pt; line-height: 1.6; vertical-align: baseline; font-family: 돋움, dotum; letter-spacing: 0pt; color: rgb(0, 0, 0);">`<span style="box-sizing: border-box; margin: 0px; padding: 0px; -webkit-font-smoothing: antialiased; -webkit-print-color-adjust: exact; border: 0px; font-style: inherit; font-variant: inherit; font-weight: inherit; font-stretch: inherit; font-size: 11pt; line-height: 1.6; vertical-align: baseline; font-family: 돋움, dotum; letter-spacing: -0.02em; color: rgb(0, 0, 0);">임상연구저널&nbsp;<span style="box-sizing: border-box; margin: 0px; padding: 0px; -webkit-font-smoothing: antialiased; -webkit-print-color-adjust: exact; border: 0px; font-style: inherit; font-variant: inherit; font-weight: inherit; font-stretch: inherit; font-size: 11pt; line-height: 1.6; vertical-align: baseline; font-family: 돋움, dotum; letter-spacing: 0pt; color: rgb(0, 0, 0);">(Journal of Clinical Investigation)' 10<span style="box-sizing: border-box; margin: 0px; padding: 0px; -webkit-font-smoothing: antialiased; -webkit-print-color-adjust: exact; border: 0px; font-style: inherit; font-variant: inherit; font-weight: inherit; font-stretch: inherit; font-size: 11pt; line-height: 1.6; vertical-align: baseline; font-family: 돋움, dotum; letter-spacing: -0.02em; color: rgb(0, 0, 0);">월&nbsp;<span style="box-sizing: border-box; margin: 0px; padding: 0px; -webkit-font-smoothing: antialiased; -webkit-print-color-adjust: exact; border: 0px; font-style: inherit; font-variant: inherit; font-weight: inherit; font-stretch: inherit; font-size: 11pt; line-height: 1.6; vertical-align: baseline; font-family: 돋움, dotum; letter-spacing: 0pt; color: rgb(0, 0, 0);">7<span style="box-sizing: border-box; margin: 0px; padding: 0px; -webkit-font-smoothing: antialiased; -webkit-print-color-adjust: exact; border: 0px; font-style: inherit; font-variant: inherit; font-weight: inherit; font-stretch: inherit; font-size: 11pt; line-height: 1.6; vertical-align: baseline; font-family: 돋움, dotum; letter-spacing: -0.02em; color: rgb(0, 0, 0);">일&nbsp;<span style="box-sizing: border-box; margin: 0px; padding: 0px; -webkit-font-smoothing: antialiased; -webkit-print-color-adjust: exact; border: 0px; font-style: inherit; font-variant: inherit; font-weight: inherit; font-stretch: inherit; font-size: 11pt; line-height: 1.6; vertical-align: baseline; font-family: 돋움, dotum; letter-spacing: 0pt; color: rgb(0, 0, 0);">字&nbsp;<span style="box-sizing: border-box; margin: 0px; padding: 0px; -webkit-font-smoothing: antialiased; -webkit-print-color-adjust: exact; border: 0px; font-style: inherit; font-variant: inherit; font-weight: inherit; font-stretch: inherit; font-size: 11pt; line-height: 1.6; vertical-align: baseline; font-family: 돋움, dotum; letter-spacing: -0.02em; color: rgb(0, 0, 0);">온라인판에 출판됐다<span style="box-sizing: border-box; margin: 0px; padding: 0px; -webkit-font-smoothing: antialiased; -webkit-print-color-adjust: exact; border: 0px; font-style: inherit; font-variant: inherit; font-weight: inherit; font-stretch: inherit; font-size: 11pt; line-height: 1.6; vertical-align: baseline; font-family: 돋움, dotum; letter-spacing: 0pt; color: rgb(0, 0, 0);">. (<span style="box-sizing: border-box; margin: 0px; padding: 0px; -webkit-font-smoothing: antialiased; -webkit-print-color-adjust: exact; border: 0px; font-style: inherit; font-variant: inherit; font-weight: inherit; font-stretch: inherit; font-size: 11pt; line-height: 1.6; vertical-align: baseline; font-family: 돋움, dotum; letter-spacing: -0.02em; color: rgb(0, 0, 0);">논문명&nbsp;<span style="box-sizing: border-box; margin: 0px; padding: 0px; -webkit-font-smoothing: antialiased; -webkit-print-color-adjust: exact; border: 0px; font-style: inherit; font-variant: inherit; font-weight: inherit; font-stretch: inherit; font-size: 11pt; line-height: 1.6; vertical-align: baseline; font-family: 돋움, dotum; letter-spacing: 0pt; color: rgb(0, 0, 0);">:&nbsp;<span style="box-sizing: border-box; margin: 0px; padding: 0px; -webkit-font-smoothing: antialiased; -webkit-print-color-adjust: exact; border: 0px; font-style: italic; font-variant: inherit; font-weight: inherit; font-stretch: inherit; font-size: 11pt; line-height: 1.6; vertical-align: baseline; font-family: 돋움, dotum; letter-spacing: 0pt; color: rgb(0, 0, 0);">Inhibiting serotonin signaling through HTR2B in visceral adipose tissue improve obesity induced insulin resistance&nbsp;<span style="box-sizing: border-box; margin: 0px; padding: 0px; -webkit-font-smoothing: antialiased; -webkit-print-color-adjust: exact; border: 0px; font-style: inherit; font-variant: inherit; font-weight: inherit; font-stretch: inherit; font-size: 11pt; line-height: 1.6; vertical-align: baseline; font-family: 돋움, dotum; letter-spacing: 0pt; color: rgb(0, 0, 0);">)<span style="box-sizing: border-box; margin: 0px; padding: 0px; -webkit-font-smoothing: antialiased; -webkit-print-color-adjust: exact; border: 0px; font-style: inherit; font-variant: inherit; font-weight: inherit; font-stretch: inherit; font-size: 11pt; line-height: 1.6; vertical-align: baseline; font-family: 돋움, dotum; letter-spacing: -0.02em; color: rgb(0, 0, 0);">&nbsp;<p class="0" style="box-sizing: border-box; margin-top: 20px; margin-bottom: 20px; -webkit-font-smoothing: antialiased; -webkit-print-color-adjust: exact; border: 0px; font-variant-numeric: inherit; font-variant-east-asian: inherit; font-stretch: inherit; font-size: 16px; line-height: 24px; vertical-align: baseline; font-family: "Noto Sans CJK KR", "Noto Sans KR", "Noto Sans EOT", SimHei, sans-serif, 맑은고딕, "Malgun Gothic", -apple-system, BlinkMacSystemFont, "Segoe UI", Roboto, "Helvetica Neue", Arial, sans-serif, FangSong, 仿宋, STFangSong, 华文仿宋, "Apple Color Emoji", "Segoe UI Emoji", "Segoe UI Symbol", AppleGothic, Dotum, arial, sans-serif; letter-spacing: -0.02em; overflow-wrap: break-word; color: rgb(102, 102, 102); text-align: justify;" align="justify"><span style="box-sizing: border-box; margin: 0px; padding: 0px; -webkit-font-smoothing: antialiased; -webkit-print-color-adjust: exact; border: 0px; font-style: inherit; font-variant: inherit; font-weight: inherit; font-stretch: inherit; font-size: 11pt; line-height: 1.6; vertical-align: baseline; font-family: 돋움, dotum; letter-spacing: -0.02em; color: rgb(0, 0, 0);">세로토닌은 뇌에서의 역할과 달리 말초조직에서 비만<span style="box-sizing: border-box; margin: 0px; padding: 0px; -webkit-font-smoothing: antialiased; -webkit-print-color-adjust: exact; border: 0px; font-style: inherit; font-variant: inherit; font-weight: inherit; font-stretch: inherit; font-size: 11pt; line-height: 1.6; vertical-align: baseline; font-family: 돋움, dotum; letter-spacing: 0pt; color: rgb(0, 0, 0);">,&nbsp;<span style="box-sizing: border-box; margin: 0px; padding: 0px; -webkit-font-smoothing: antialiased; -webkit-print-color-adjust: exact; border: 0px; font-style: inherit; font-variant: inherit; font-weight: inherit; font-stretch: inherit; font-size: 11pt; line-height: 1.6; vertical-align: baseline; font-family: 돋움, dotum; letter-spacing: -0.02em; color: rgb(0, 0, 0);">당뇨 상황에서 다양한 에너지대사를 조절한다<span style="box-sizing: border-box; margin: 0px; padding: 0px; -webkit-font-smoothing: antialiased; -webkit-print-color-adjust: exact; border: 0px; font-style: inherit; font-variant: inherit; font-weight: inherit; font-stretch: inherit; font-size: 11pt; line-height: 1.6; vertical-align: baseline; font-family: 돋움, dotum; letter-spacing: 0pt; color: rgb(0, 0, 0);">.&nbsp;<span style="box-sizing: border-box; margin: 0px; padding: 0px; -webkit-font-smoothing: antialiased; -webkit-print-color-adjust: exact; border: 0px; font-style: inherit; font-variant: inherit; font-weight: inherit; font-stretch: inherit; font-size: 11pt; line-height: 1.6; vertical-align: baseline; font-family: 돋움, dotum; letter-spacing: -0.02em; color: rgb(0, 0, 0);">특히 간조직의 세로토닌 신호전달은 지방 합성을 촉진한다고 알려져 있으며<span style="box-sizing: border-box; margin: 0px; padding: 0px; -webkit-font-smoothing: antialiased; -webkit-print-color-adjust: exact; border: 0px; font-style: inherit; font-variant: inherit; font-weight: inherit; font-stretch: inherit; font-size: 11pt; line-height: 1.6; vertical-align: baseline; font-family: 돋움, dotum; letter-spacing: 0pt; color: rgb(0, 0, 0);">,&nbsp;<span style="box-sizing: border-box; margin: 0px; padding: 0px; -webkit-font-smoothing: antialiased; -webkit-print-color-adjust: exact; border: 0px; font-style: inherit; font-variant: inherit; font-weight: inherit; font-stretch: inherit; font-size: 11pt; line-height: 1.6; vertical-align: baseline; font-family: 돋움, dotum; letter-spacing: -0.02em; color: rgb(0, 0, 0);">이 신호를 억제하였을 때 지방간 형성이 개선되는 것을 확인한 바 있다<span style="box-sizing: border-box; margin: 0px; padding: 0px; -webkit-font-smoothing: antialiased; -webkit-print-color-adjust: exact; border: 0px; font-style: inherit; font-variant: inherit; font-weight: inherit; font-stretch: inherit; font-size: 11pt; line-height: 1.6; vertical-align: baseline; font-family: 돋움, dotum; letter-spacing: 0pt; color: rgb(0, 0, 0);">.&nbsp;<span style="box-sizing: border-box; margin: 0px; padding: 0px; -webkit-font-smoothing: antialiased; -webkit-print-color-adjust: exact; border: 0px; font-style: inherit; font-variant: inherit; font-weight: inherit; font-stretch: inherit; font-size: 11pt; line-height: 1.6; vertical-align: baseline; font-family: 돋움, dotum; letter-spacing: -0.02em; color: rgb(0, 0, 0);">이에 공동연구팀은 세로토닌의 내장지방에서의 역할을 확인해 보기로 하였고<span style="box-sizing: border-box; margin: 0px; padding: 0px; -webkit-font-smoothing: antialiased; -webkit-print-color-adjust: exact; border: 0px; font-style: inherit; font-variant: inherit; font-weight: inherit; font-stretch: inherit; font-size: 11pt; line-height: 1.6; vertical-align: baseline; font-family: 돋움, dotum; letter-spacing: 0pt; color: rgb(0, 0, 0);">,&nbsp;<span style="box-sizing: border-box; margin: 0px; padding: 0px; -webkit-font-smoothing: antialiased; -webkit-print-color-adjust: exact; border: 0px; font-style: inherit; font-variant: inherit; font-weight: inherit; font-stretch: inherit; font-size: 11pt; line-height: 1.6; vertical-align: baseline; font-family: 돋움, dotum; letter-spacing: -0.02em; color: rgb(0, 0, 0);">지방세포에서 세로토닌&nbsp;<span style="box-sizing: border-box; margin: 0px; padding: 0px; -webkit-font-smoothing: antialiased; -webkit-print-color-adjust: exact; border: 0px; font-style: inherit; font-variant: inherit; font-weight: inherit; font-stretch: inherit; font-size: 11pt; line-height: 1.6; vertical-align: baseline; font-family: 돋움, dotum; letter-spacing: 0pt; color: rgb(0, 0, 0);">2B&nbsp;<span style="box-sizing: border-box; margin: 0px; padding: 0px; -webkit-font-smoothing: antialiased; -webkit-print-color-adjust: exact; border: 0px; font-style: inherit; font-variant: inherit; font-weight: inherit; font-stretch: inherit; font-size: 11pt; line-height: 1.6; vertical-align: baseline; font-family: 돋움, dotum; letter-spacing: -0.02em; color: rgb(0, 0, 0);">수용체의 신호를 억제하면 지방조직 내 염증반응이 감소하고<span style="box-sizing: border-box; margin: 0px; padding: 0px; -webkit-font-smoothing: antialiased; -webkit-print-color-adjust: exact; border: 0px; font-style: inherit; font-variant: inherit; font-weight: inherit; font-stretch: inherit; font-size: 11pt; line-height: 1.6; vertical-align: baseline; font-family: 돋움, dotum; letter-spacing: 0pt; color: rgb(0, 0, 0);">,&nbsp;<span style="box-sizing: border-box; margin: 0px; padding: 0px; -webkit-font-smoothing: antialiased; -webkit-print-color-adjust: exact; border: 0px; font-style: inherit; font-variant: inherit; font-weight: inherit; font-stretch: inherit; font-size: 11pt; line-height: 1.6; vertical-align: baseline; font-family: 돋움, dotum; letter-spacing: -0.02em; color: rgb(0, 0, 0);">지방간 억제 및 전신적 인슐린 감수성 증가 등 전반적인 대사 지표가 개선되는 효과를 확인하였다<span style="box-sizing: border-box; margin: 0px; padding: 0px; -webkit-font-smoothing: antialiased; -webkit-print-color-adjust: exact; border: 0px; font-style: inherit; font-variant: inherit; font-weight: inherit; font-stretch: inherit; font-size: 11pt; line-height: 1.6; vertical-align: baseline; font-family: 돋움, dotum; letter-spacing: 0pt; color: rgb(0, 0, 0);">.&nbsp;<span style="box-sizing: border-box; margin: 0px; padding: 0px; -webkit-font-smoothing: antialiased; -webkit-print-color-adjust: exact; border: 0px; font-style: inherit; font-variant: inherit; font-weight: inherit; font-stretch: inherit; font-size: 11pt; line-height: 1.6; vertical-align: baseline; font-family: 돋움, dotum; letter-spacing: -0.02em; color: rgb(0, 0, 0);">이는 세로토닌이 중추신경을 통해서가 아니라 직접적으로 지방조직에 작용한다는 것을 새롭게 발견한 것으로<span style="box-sizing: border-box; margin: 0px; padding: 0px; -webkit-font-smoothing: antialiased; -webkit-print-color-adjust: exact; border: 0px; font-style: inherit; font-variant: inherit; font-weight: inherit; font-stretch: inherit; font-size: 11pt; line-height: 1.6; vertical-align: baseline; font-family: 돋움, dotum; letter-spacing: 0pt; color: rgb(0, 0, 0);">,&nbsp;<span style="box-sizing: border-box; margin: 0px; padding: 0px; -webkit-font-smoothing: antialiased; -webkit-print-color-adjust: exact; border: 0px; font-style: inherit; font-variant: inherit; font-weight: inherit; font-stretch: inherit; font-size: 11pt; line-height: 1.6; vertical-align: baseline; font-family: 돋움, dotum; letter-spacing: -0.02em; color: rgb(0, 0, 0);">향후 새로운 당뇨병 및 지방간 치료제 개발의 표적을 제시하였다는 데에 의의가 있다<span style="box-sizing: border-box; margin: 0px; padding: 0px; -webkit-font-smoothing: antialiased; -webkit-print-color-adjust: exact; border: 0px; font-style: inherit; font-variant: inherit; font-weight: inherit; font-stretch: inherit; font-size: 11pt; line-height: 1.6; vertical-align: baseline; font-family: 돋움, dotum; letter-spacing: 0pt; color: rgb(0, 0, 0);">.<span style="box-sizing: border-box; margin: 0px; padding: 0px; -webkit-font-smoothing: antialiased; -webkit-print-color-adjust: exact; border: 0px; font-style: inherit; font-variant: inherit; font-weight: inherit; font-stretch: inherit; font-size: 11pt; line-height: 1.6; vertical-align: baseline; font-family: 돋움, dotum; letter-spacing: -0.02em; color: rgb(0, 0, 0);">&nbsp;<p class="0" style="box-sizing: border-box; margin-top: 20px; margin-bottom: 20px; -webkit-font-smoothing: antialiased; -webkit-print-color-adjust: exact; border: 0px; font-variant-numeric: inherit; font-variant-east-asian: inherit; font-stretch: inherit; font-size: 16px; line-height: 24px; vertical-align: baseline; font-family: "Noto Sans CJK KR", "Noto Sans KR", "Noto Sans EOT", SimHei, sans-serif, 맑은고딕, "Malgun Gothic", -apple-system, BlinkMacSystemFont, "Segoe UI", Roboto, "Helvetica Neue", Arial, sans-serif, FangSong, 仿宋, STFangSong, 华文仿宋, "Apple Color Emoji", "Segoe UI Emoji", "Segoe UI Symbol", AppleGothic, Dotum, arial, sans-serif; letter-spacing: -0.02em; overflow-wrap: break-word; color: rgb(102, 102, 102); text-align: justify;" align="justify"><span style="box-sizing: border-box; margin: 0px; padding: 0px; -webkit-font-smoothing: antialiased; -webkit-print-color-adjust: exact; border: 0px; font-style: inherit; font-variant: inherit; font-weight: inherit; font-stretch: inherit; font-size: 11pt; line-height: 1.6; vertical-align: baseline; font-family: 돋움, dotum; letter-spacing: -0.02em; color: rgb(0, 0, 0);">세로토닌 신호 억제를 주요 표적으로 한 지방간 혹은 당뇨병 치료제 개발은 생물학적<span style="box-sizing: border-box; margin: 0px; padding: 0px; -webkit-font-smoothing: antialiased; -webkit-print-color-adjust: exact; border: 0px; font-style: inherit; font-variant: inherit; font-weight: inherit; font-stretch: inherit; font-size: 11pt; line-height: 1.6; vertical-align: baseline; font-family: 돋움, dotum; letter-spacing: 0pt; color: rgb(0, 0, 0);">,&nbsp;<span style="box-sizing: border-box; margin: 0px; padding: 0px; -webkit-font-smoothing: antialiased; -webkit-print-color-adjust: exact; border: 0px; font-style: inherit; font-variant: inherit; font-weight: inherit; font-stretch: inherit; font-size: 11pt; line-height: 1.6; vertical-align: baseline; font-family: 돋움, dotum; letter-spacing: -0.02em; color: rgb(0, 0, 0);">임상적으로 중요한 의미를 가진다<span style="box-sizing: border-box; margin: 0px; padding: 0px; -webkit-font-smoothing: antialiased; -webkit-print-color-adjust: exact; border: 0px; font-style: inherit; font-variant: inherit; font-weight: inherit; font-stretch: inherit; font-size: 11pt; line-height: 1.6; vertical-align: baseline; font-family: 돋움, dotum; letter-spacing: 0pt; color: rgb(0, 0, 0);">.&nbsp;<span style="box-sizing: border-box; margin: 0px; padding: 0px; -webkit-font-smoothing: antialiased; -webkit-print-color-adjust: exact; border: 0px; font-style: inherit; font-variant: inherit; font-weight: inherit; font-stretch: inherit; font-size: 11pt; line-height: 1.6; vertical-align: baseline; font-family: 돋움, dotum; letter-spacing: -0.02em; color: rgb(0, 0, 0);">기존에 개발된 치료제들과 달리 지방조직과 간조직을 동시에 표적으로 하는 세로토닌 신호 억제제는 향후 대사질환 치료제 개발 연구분야에서 괄목할만한 성과를 보일 것으로 기대된다<span style="box-sizing: border-box; margin: 0px; padding: 0px; -webkit-font-smoothing: antialiased; -webkit-print-color-adjust: exact; border: 0px; font-style: inherit; font-variant: inherit; font-weight: inherit; font-stretch: inherit; font-size: 11pt; line-height: 1.6; vertical-align: baseline; font-family: 돋움, dotum; letter-spacing: 0pt; color: rgb(0, 0, 0);">.<span style="box-sizing: border-box; margin: 0px; padding: 0px; -webkit-font-smoothing: antialiased; -webkit-print-color-adjust: exact; border: 0px; font-style: inherit; font-variant: inherit; font-weight: inherit; font-stretch: inherit; font-size: 11pt; line-height: 1.6; vertical-align: baseline; font-family: 돋움, dotum; letter-spacing: -0.02em; color: rgb(0, 0, 0);">&nbsp;<p class="0" style="text-align: center; box-sizing: border-box; margin-top: 20px; margin-bottom: 20px; -webkit-font-smoothing: antialiased; -webkit-print-color-adjust: exact; border: 0px; font-variant-numeric: inherit; font-variant-east-asian: inherit; font-stretch: inherit; font-size: 16px; line-height: 24px; vertical-align: baseline; font-family: "Noto Sans CJK KR", "Noto Sans KR", "Noto Sans EOT", SimHei, sans-serif, 맑은고딕, "Malgun Gothic", -apple-system, BlinkMacSystemFont, "Segoe UI", Roboto, "Helvetica Neue", Arial, sans-serif, FangSong, 仿宋, STFangSong, 华文仿宋, "Apple Color Emoji", "Segoe UI Emoji", "Segoe UI Symbol", AppleGothic, Dotum, arial, sans-serif; letter-spacing: -0.02em; overflow-wrap: break-word; color: rgb(102, 102, 102);" align="center"><a href="https://news.kaist.ac.kr/news/html/news/?mode=V&mng_no=16391&skey=category&sval=%EC%97%B0%EA%B5%AC&list_s_date=&list_e_date=&GotoPage=1" target="_blank"><img src="https://news.kaist.ac.kr/_prog/download/?editor_image=/images/000038/image1.jpg_14.jpg" title="그림 1. 비만시에 지방세포의 세로토닌 2B 신호전달에 의한 생체 내 조직의 변화 모식도" alt="그림 1. 비만시에 지방세포의 세로토닌 2B 신호전달에 의한 생체 내 조직의 변화 모식도" style="box-sizing: border-box; margin: 0px; padding: 0px; -webkit-font-smoothing: antialiased; -webkit-print-color-adjust: exact; border: 0px solid rgb(0, 0, 0); font-style: inherit; font-variant: inherit; font-weight: inherit; font-stretch: inherit; font-size: inherit; line-height: inherit; vertical-align: middle; letter-spacing: -0.02em; -webkit-tap-highlight-color: transparent; max-width: 100%; width: 350px; height: 471px;"></a><p style="text-align: justify; box-sizing: border-box; margin-top: 20px; margin-bottom: 20px; -webkit-font-smoothing: antialiased; -webkit-print-color-adjust: exact; border: 0px; font-variant-numeric: inherit; font-variant-east-asian: inherit; font-stretch: inherit; font-size: 16px; line-height: 24px; vertical-align: baseline; font-family: "Noto Sans CJK KR", "Noto Sans KR", "Noto Sans EOT", SimHei, sans-serif, 맑은고딕, "Malgun Gothic", -apple-system, BlinkMacSystemFont, "Segoe UI", Roboto, "Helvetica Neue", Arial, sans-serif, FangSong, 仿宋, STFangSong, 华文仿宋, "Apple Color Emoji", "Segoe UI Emoji", "Segoe UI Symbol", AppleGothic, Dotum, arial, sans-serif; letter-spacing: -0.02em; overflow-wrap: break-word; color: rgb(102, 102, 102);" align="justify">< 그림 1. 비만시에 지방세포의 세로토닌 2B 신호전달에 의한 생체 내 조직의 변화 모식도 ><p style="box-sizing: border-box; margin-top: 20px; margin-bottom: 20px; -webkit-font-smoothing: antialiased; -webkit-print-color-adjust: exact; border: 0px; font-variant-numeric: inherit; font-variant-east-asian: inherit; font-stretch: inherit; font-size: 16px; line-height: 24px; vertical-align: baseline; font-family: "Noto Sans CJK KR", "Noto Sans KR", "Noto Sans EOT", SimHei, sans-serif, 맑은고딕, "Malgun Gothic", -apple-system, BlinkMacSystemFont, "Segoe UI", Roboto, "Helvetica Neue", Arial, sans-serif, FangSong, 仿宋, STFangSong, 华文仿宋, "Apple Color Emoji", "Segoe UI Emoji", "Segoe UI Symbol", AppleGothic, Dotum, arial, sans-serif; letter-spacing: -0.02em; overflow-wrap: break-word; color: rgb(102, 102, 102);">&nbsp;<p class="0" style="box-sizing: border-box; margin-top: 20px; margin-bottom: 20px; -webkit-font-smoothing: antialiased; -webkit-print-color-adjust: exact; border: 0px; font-variant-numeric: inherit; font-variant-east-asian: inherit; font-stretch: inherit; font-size: 16px; line-height: 24px; vertical-align: baseline; font-family: "Noto Sans CJK KR", "Noto Sans KR", "Noto Sans EOT", SimHei, sans-serif, 맑은고딕, "Malgun Gothic", -apple-system, BlinkMacSystemFont, "Segoe UI", Roboto, "Helvetica Neue", Arial, sans-serif, FangSong, 仿宋, STFangSong, 华文仿宋, "Apple Color Emoji", "Segoe UI Emoji", "Segoe UI Symbol", AppleGothic, Dotum, arial, sans-serif; letter-spacing: -0.02em; overflow-wrap: break-word; color: rgb(102, 102, 102); text-align: justify;" align="justify"><span style="box-sizing: border-box; margin: 0px; padding: 0px; -webkit-font-smoothing: antialiased; -webkit-print-color-adjust: exact; border: 0px; font-style: inherit; font-variant: inherit; font-weight: inherit; font-stretch: inherit; font-size: 11pt; line-height: 1.6; vertical-align: baseline; font-family: 돋움, dotum; letter-spacing: -0.02em; color: rgb(0, 0, 0);">비만이 당뇨병 및 지방간과 같은 만성질환을 유발하는 데에 내장지방의 양적 증가와 대사 변화가 중요할 것이라는 점은 학계에서 널리 받아들여지고 있는 현상이다<span style="box-sizing: border-box; margin: 0px; padding: 0px; -webkit-font-smoothing: antialiased; -webkit-print-color-adjust: exact; border: 0px; font-style: inherit; font-variant: inherit; font-weight: inherit; font-stretch: inherit; font-size: 11pt; line-height: 1.6; vertical-align: baseline; font-family: 돋움, dotum; letter-spacing: 0pt; color: rgb(0, 0, 0);">.&nbsp;<span style="box-sizing: border-box; margin: 0px; padding: 0px; -webkit-font-smoothing: antialiased; -webkit-print-color-adjust: exact; border: 0px; font-style: inherit; font-variant: inherit; font-weight: inherit; font-stretch: inherit; font-size: 11pt; line-height: 1.6; vertical-align: baseline; font-family: 돋움, dotum; letter-spacing: -0.02em; color: rgb(0, 0, 0);">본 연구는 세로토닌&nbsp;<span style="box-sizing: border-box; margin: 0px; padding: 0px; -webkit-font-smoothing: antialiased; -webkit-print-color-adjust: exact; border: 0px; font-style: inherit; font-variant: inherit; font-weight: inherit; font-stretch: inherit; font-size: 11pt; line-height: 1.6; vertical-align: baseline; font-family: 돋움, dotum; letter-spacing: 0pt; color: rgb(0, 0, 0);">2B&nbsp;<span style="box-sizing: border-box; margin: 0px; padding: 0px; -webkit-font-smoothing: antialiased; -webkit-print-color-adjust: exact; border: 0px; font-style: inherit; font-variant: inherit; font-weight: inherit; font-stretch: inherit; font-size: 11pt; line-height: 1.6; vertical-align: baseline; font-family: 돋움, dotum; letter-spacing: -0.02em; color: rgb(0, 0, 0);">수용체가 비만과 같은 인슐린 저항성이 유발되는 상황에서 내장지방 특이적으로 발현이 증가한다는 관찰에서 시작되었으며<span style="box-sizing: border-box; margin: 0px; padding: 0px; -webkit-font-smoothing: antialiased; -webkit-print-color-adjust: exact; border: 0px; font-style: inherit; font-variant: inherit; font-weight: inherit; font-stretch: inherit; font-size: 11pt; line-height: 1.6; vertical-align: baseline; font-family: 돋움, dotum; letter-spacing: 0pt; color: rgb(0, 0, 0);">,&nbsp;<span style="box-sizing: border-box; margin: 0px; padding: 0px; -webkit-font-smoothing: antialiased; -webkit-print-color-adjust: exact; border: 0px; font-style: inherit; font-variant: inherit; font-weight: inherit; font-stretch: inherit; font-size: 11pt; line-height: 1.6; vertical-align: baseline; font-family: 돋움, dotum; letter-spacing: -0.02em; color: rgb(0, 0, 0);">사람의 지방조직 및 다양한 마우스 모델을 이용하여 다학제적 접근으로 임상적인 의미를 잘 파고든 연구라는 점에서 높은 가치를 지닌다<span style="box-sizing: border-box; margin: 0px; padding: 0px; -webkit-font-smoothing: antialiased; -webkit-print-color-adjust: exact; border: 0px; font-style: inherit; font-variant: inherit; font-weight: inherit; font-stretch: inherit; font-size: 11pt; line-height: 1.6; vertical-align: baseline; font-family: 돋움, dotum; letter-spacing: 0pt; color: rgb(0, 0, 0);">.<p class="0" style="text-align: center; box-sizing: border-box; margin-top: 20px; margin-bottom: 20px; -webkit-font-smoothing: antialiased; -webkit-print-color-adjust: exact; border: 0px; font-variant-numeric: inherit; font-variant-east-asian: inherit; font-stretch: inherit; font-size: 16px; line-height: 24px; vertical-align: baseline; font-family: "Noto Sans CJK KR", "Noto Sans KR", "Noto Sans EOT", SimHei, sans-serif, 맑은고딕, "Malgun Gothic", -apple-system, BlinkMacSystemFont, "Segoe UI", Roboto, "Helvetica Neue", Arial, sans-serif, FangSong, 仿宋, STFangSong, 华文仿宋, "Apple Color Emoji", "Segoe UI Emoji", "Segoe UI Symbol", AppleGothic, Dotum, arial, sans-serif; letter-spacing: -0.02em; overflow-wrap: break-word; color: rgb(102, 102, 102);" align="center"><a href="https://news.kaist.ac.kr/news/html/news/?mode=V&mng_no=16391&skey=category&sval=%EC%97%B0%EA%B5%AC&list_s_date=&list_e_date=&GotoPage=1" target="_blank"><img src="https://news.kaist.ac.kr/_prog/download/?editor_image=/images/000038/image2.jpg_8.jpg" title="그림 2. 사람의 내장지방에서 세로토닌 수용체 2B 발현양과 BMI, AST, ALT(간지표)와의 상관관계 등" alt="그림 2. 사람의 내장지방에서 세로토닌 수용체 2B 발현양과 BMI, AST, ALT(간지표)와의 상관관계 등" style="box-sizing: border-box; margin: 0px; padding: 0px; -webkit-font-smoothing: antialiased; -webkit-print-color-adjust: exact; border: 0px solid rgb(0, 0, 0); font-style: inherit; font-variant: inherit; font-weight: inherit; font-stretch: inherit; font-size: inherit; line-height: inherit; vertical-align: middle; letter-spacing: -0.02em; -webkit-tap-highlight-color: transparent; max-width: 100%; width: 700px; height: 442px;"></a><p style="text-align: justify; box-sizing: border-box; margin-top: 20px; margin-bottom: 20px; -webkit-font-smoothing: antialiased; -webkit-print-color-adjust: exact; border: 0px; font-variant-numeric: inherit; font-variant-east-asian: inherit; font-stretch: inherit; font-size: 16px; line-height: 24px; vertical-align: baseline; font-family: "Noto Sans CJK KR", "Noto Sans KR", "Noto Sans EOT", SimHei, sans-serif, 맑은고딕, "Malgun Gothic", -apple-system, BlinkMacSystemFont, "Segoe UI", Roboto, "Helvetica Neue", Arial, sans-serif, FangSong, 仿宋, STFangSong, 华文仿宋, "Apple Color Emoji", "Segoe UI Emoji", "Segoe UI Symbol", AppleGothic, Dotum, arial, sans-serif; letter-spacing: -0.02em; overflow-wrap: break-word; color: rgb(102, 102, 102);" align="justify">< 그림 2. 사람의 내장지방에서 세로토닌 수용체 2B 발현양과 BMI, AST, ALT(간지표)와의 상관관계 등 ><p style="box-sizing: border-box; margin-top: 20px; margin-bottom: 20px; -webkit-font-smoothing: antialiased; -webkit-print-color-adjust: exact; border: 0px; font-variant-numeric: inherit; font-variant-east-asian: inherit; font-stretch: inherit; font-size: 16px; line-height: 24px; vertical-align: baseline; font-family: "Noto Sans CJK KR", "Noto Sans KR", "Noto Sans EOT", SimHei, sans-serif, 맑은고딕, "Malgun Gothic", -apple-system, BlinkMacSystemFont, "Segoe UI", Roboto, "Helvetica Neue", Arial, sans-serif, FangSong, 仿宋, STFangSong, 华文仿宋, "Apple Color Emoji", "Segoe UI Emoji", "Segoe UI Symbol", AppleGothic, Dotum, arial, sans-serif; letter-spacing: -0.02em; overflow-wrap: break-word; color: rgb(102, 102, 102);">&nbsp;<p class="0" style="box-sizing: border-box; margin-top: 20px; margin-bottom: 20px; -webkit-font-smoothing: antialiased; -webkit-print-color-adjust: exact; border: 0px; font-variant-numeric: inherit; font-variant-east-asian: inherit; font-stretch: inherit; font-size: 16px; line-height: 24px; vertical-align: baseline; font-family: "Noto Sans CJK KR", "Noto Sans KR", "Noto Sans EOT", SimHei, sans-serif, 맑은고딕, "Malgun Gothic", -apple-system, BlinkMacSystemFont, "Segoe UI", Roboto, "Helvetica Neue", Arial, sans-serif, FangSong, 仿宋, STFangSong, 华文仿宋, "Apple Color Emoji", "Segoe UI Emoji", "Segoe UI Symbol", AppleGothic, Dotum, arial, sans-serif; letter-spacing: -0.02em; overflow-wrap: break-word; color: rgb(102, 102, 102); text-align: justify;" align="justify"><span style="box-sizing: border-box; margin: 0px; padding: 0px; -webkit-font-smoothing: antialiased; -webkit-print-color-adjust: exact; border: 0px; font-style: inherit; font-variant: inherit; font-weight: inherit; font-stretch: inherit; font-size: 11pt; line-height: 1.6; vertical-align: baseline; font-family: 돋움, dotum; letter-spacing: -0.02em; color: rgb(0, 0, 0);">공동 제<span style="box-sizing: border-box; margin: 0px; padding: 0px; -webkit-font-smoothing: antialiased; -webkit-print-color-adjust: exact; border: 0px; font-style: inherit; font-variant: inherit; font-weight: inherit; font-stretch: inherit; font-size: 11pt; line-height: 1.6; vertical-align: baseline; font-family: 돋움, dotum; letter-spacing: 0pt; color: rgb(0, 0, 0);">1&nbsp;<span style="box-sizing: border-box; margin: 0px; padding: 0px; -webkit-font-smoothing: antialiased; -webkit-print-color-adjust: exact; border: 0px; font-style: inherit; font-variant: inherit; font-weight: inherit; font-stretch: inherit; font-size: 11pt; line-height: 1.6; vertical-align: baseline; font-family: 돋움, dotum; letter-spacing: -0.02em; color: rgb(0, 0, 0);">저자인 우리 대학&nbsp;최원근 박사는&nbsp;<span style="box-sizing: border-box; margin: 0px; padding: 0px; -webkit-font-smoothing: antialiased; -webkit-print-color-adjust: exact; border: 0px; font-style: inherit; font-variant: inherit; font-weight: inherit; font-stretch: inherit; font-size: 11pt; line-height: 1.6; vertical-align: baseline; font-family: 돋움, dotum; letter-spacing: 0pt; color: rgb(0, 0, 0);">"<span style="box-sizing: border-box; margin: 0px; padding: 0px; -webkit-font-smoothing: antialiased; -webkit-print-color-adjust: exact; border: 0px; font-style: inherit; font-variant: inherit; font-weight: inherit; font-stretch: inherit; font-size: 11pt; line-height: 1.6; vertical-align: baseline; font-family: 돋움, dotum; letter-spacing: -0.02em; color: rgb(0, 0, 0);">이번 연구를 통해 세로토닌 수용체를 표적으로 한 약물이 지방간을 포함한 다양한 대사질환 치료에 새로운 지평을 열 것으로 사료된다<span style="box-sizing: border-box; margin: 0px; padding: 0px; -webkit-font-smoothing: antialiased; -webkit-print-color-adjust: exact; border: 0px; font-style: inherit; font-variant: inherit; font-weight: inherit; font-stretch: inherit; font-size: 11pt; line-height: 1.6; vertical-align: baseline; font-family: 돋움, dotum; letter-spacing: 0pt; color: rgb(0, 0, 0);">"<span style="box-sizing: border-box; margin: 0px; padding: 0px; -webkit-font-smoothing: antialiased; -webkit-print-color-adjust: exact; border: 0px; font-style: inherit; font-variant: inherit; font-weight: inherit; font-stretch: inherit; font-size: 11pt; line-height: 1.6; vertical-align: baseline; font-family: 돋움, dotum; letter-spacing: -0.02em; color: rgb(0, 0, 0);">고 말했다<span style="box-sizing: border-box; margin: 0px; padding: 0px; -webkit-font-smoothing: antialiased; -webkit-print-color-adjust: exact; border: 0px; font-style: inherit; font-variant: inherit; font-weight: inherit; font-stretch: inherit; font-size: 11pt; line-height: 1.6; vertical-align: baseline; font-family: 돋움, dotum; letter-spacing: 0pt; color: rgb(0, 0, 0);">.&nbsp;<span style="box-sizing: border-box; margin: 0px; padding: 0px; -webkit-font-smoothing: antialiased; -webkit-print-color-adjust: exact; border: 0px; font-style: inherit; font-variant: inherit; font-weight: inherit; font-stretch: inherit; font-size: 11pt; line-height: 1.6; vertical-align: baseline; font-family: 돋움, dotum; letter-spacing: -0.02em; color: rgb(0, 0, 0);">또한 공동교신저자인 김하일 교수는&nbsp;<span style="box-sizing: border-box; margin: 0px; padding: 0px; -webkit-font-smoothing: antialiased; -webkit-print-color-adjust: exact; border: 0px; font-style: inherit; font-variant: inherit; font-weight: inherit; font-stretch: inherit; font-size: 11pt; line-height: 1.6; vertical-align: baseline; font-family: 돋움, dotum; letter-spacing: 0pt; color: rgb(0, 0, 0);">"<span style="box-sizing: border-box; margin: 0px; padding: 0px; -webkit-font-smoothing: antialiased; -webkit-print-color-adjust: exact; border: 0px; font-style: inherit; font-variant: inherit; font-weight: inherit; font-stretch: inherit; font-size: 11pt; line-height: 1.6; vertical-align: baseline; font-family: 돋움, dotum; letter-spacing: -0.02em; color: rgb(0, 0, 0);">최근 의과학 연구분야에 있어 기초연구자와 임상의사의 협업의 중요성이 강조되는 가운데&nbsp;<span style="box-sizing: border-box; margin: 0px; padding: 0px; -webkit-font-smoothing: antialiased; -webkit-print-color-adjust: exact; border: 0px; font-style: inherit; font-variant: inherit; font-weight: inherit; font-stretch: inherit; font-size: 11pt; line-height: 1.6; vertical-align: baseline; font-family: 돋움, dotum; letter-spacing: 0pt; color: rgb(0, 0, 0);">KAIST<span style="box-sizing: border-box; margin: 0px; padding: 0px; -webkit-font-smoothing: antialiased; -webkit-print-color-adjust: exact; border: 0px; font-style: inherit; font-variant: inherit; font-weight: inherit; font-stretch: inherit; font-size: 11pt; line-height: 1.6; vertical-align: baseline; font-family: 돋움, dotum; letter-spacing: -0.02em; color: rgb(0, 0, 0);">와 분당서울대병원의 공동연구를 통해 의미있는 결론이 도출되어 기쁘다<span style="box-sizing: border-box; margin: 0px; padding: 0px; -webkit-font-smoothing: antialiased; -webkit-print-color-adjust: exact; border: 0px; font-style: inherit; font-variant: inherit; font-weight: inherit; font-stretch: inherit; font-size: 11pt; line-height: 1.6; vertical-align: baseline; font-family: 돋움, dotum; letter-spacing: 0pt; color: rgb(0, 0, 0);">"<span style="box-sizing: border-box; margin: 0px; padding: 0px; -webkit-font-smoothing: antialiased; -webkit-print-color-adjust: exact; border: 0px; font-style: inherit; font-variant: inherit; font-weight: inherit; font-stretch: inherit; font-size: 11pt; line-height: 1.6; vertical-align: baseline; font-family: 돋움, dotum; letter-spacing: -0.02em; color: rgb(0, 0, 0);">고 말했다<span style="box-sizing: border-box; margin: 0px; padding: 0px; -webkit-font-smoothing: antialiased; -webkit-print-color-adjust: exact; border: 0px; font-style: inherit; font-variant: inherit; font-weight: inherit; font-stretch: inherit; font-size: 11pt; line-height: 1.6; vertical-align: baseline; font-family: 돋움, dotum; letter-spacing: 0pt; color: rgb(0, 0, 0);">.<span style="box-sizing: border-box; margin: 0px; padding: 0px; -webkit-font-smoothing: antialiased; -webkit-print-color-adjust: exact; border: 0px; font-style: inherit; font-variant: inherit; font-weight: inherit; font-stretch: inherit; font-size: 11pt; line-height: 1.6; vertical-align: baseline; font-family: 돋움, dotum; letter-spacing: -0.5pt; color: rgb(0, 0, 0);">&nbsp;<p class="0" style="box-sizing: border-box; margin-top: 20px; margin-bottom: 20px; -webkit-font-smoothing: antialiased; -webkit-print-color-adjust: exact; border: 0px; font-variant-numeric: inherit; font-variant-east-asian: inherit; font-stretch: inherit; font-size: 16px; line-height: 24px; vertical-align: baseline; font-family: "Noto Sans CJK KR", "Noto Sans KR", "Noto Sans EOT", SimHei, sans-serif, 맑은고딕, "Malgun Gothic", -apple-system, BlinkMacSystemFont, "Segoe UI", Roboto, "Helvetica Neue", Arial, sans-serif, FangSong, 仿宋, STFangSong, 华文仿宋, "Apple Color Emoji", "Segoe UI Emoji", "Segoe UI Symbol", AppleGothic, Dotum, arial, sans-serif; letter-spacing: -0.02em; overflow-wrap: break-word; color: rgb(102, 102, 102); text-align: justify;" align="justify"><span style="box-sizing: border-box; margin: 0px; padding: 0px; -webkit-font-smoothing: antialiased; -webkit-print-color-adjust: exact; border: 0px; font-style: inherit; font-variant: inherit; font-weight: inherit; font-stretch: inherit; font-size: 11pt; line-height: 1.6; vertical-align: baseline; font-family: 돋움, dotum; letter-spacing: -0.5pt; color: rgb(0, 0, 0);">이어 공동 교신저자인 분당서울대병원 최성희 교수는&nbsp;<span style="box-sizing: border-box; margin: 0px; padding: 0px; -webkit-font-smoothing: antialiased; -webkit-print-color-adjust: exact; border: 0px; font-style: inherit; font-variant: inherit; font-weight: inherit; font-stretch: inherit; font-size: 11pt; line-height: 1.6; vertical-align: baseline; font-family: 돋움, dotum; letter-spacing: -0.5pt; color: rgb(0, 0, 0);">“<span style="box-sizing: border-box; margin: 0px; padding: 0px; -webkit-font-smoothing: antialiased; -webkit-print-color-adjust: exact; border: 0px; font-style: inherit; font-variant: inherit; font-weight: inherit; font-stretch: inherit; font-size: 11pt; line-height: 1.6; vertical-align: baseline; font-family: 돋움, dotum; letter-spacing: -0.5pt; color: rgb(0, 0, 0);">이번 연구결과를 바탕으로 세로토닌&nbsp;<span style="box-sizing: border-box; margin: 0px; padding: 0px; -webkit-font-smoothing: antialiased; -webkit-print-color-adjust: exact; border: 0px; font-style: inherit; font-variant: inherit; font-weight: inherit; font-stretch: inherit; font-size: 11pt; line-height: 1.6; vertical-align: baseline; font-family: 돋움, dotum; letter-spacing: -0.5pt; color: rgb(0, 0, 0);">2B&nbsp;<span style="box-sizing: border-box; margin: 0px; padding: 0px; -webkit-font-smoothing: antialiased; -webkit-print-color-adjust: exact; border: 0px; font-style: inherit; font-variant: inherit; font-weight: inherit; font-stretch: inherit; font-size: 11pt; line-height: 1.6; vertical-align: baseline; font-family: 돋움, dotum; letter-spacing: -0.5pt; color: rgb(0, 0, 0);">수용체 신호를 효과적으로 억제할 수 있는 치료법 개발을 통해<span style="box-sizing: border-box; margin: 0px; padding: 0px; -webkit-font-smoothing: antialiased; -webkit-print-color-adjust: exact; border: 0px; font-style: inherit; font-variant: inherit; font-weight: inherit; font-stretch: inherit; font-size: 11pt; line-height: 1.6; vertical-align: baseline; font-family: 돋움, dotum; letter-spacing: -0.5pt; color: rgb(0, 0, 0);">,&nbsp;<span style="box-sizing: border-box; margin: 0px; padding: 0px; -webkit-font-smoothing: antialiased; -webkit-print-color-adjust: exact; border: 0px; font-style: inherit; font-variant: inherit; font-weight: inherit; font-stretch: inherit; font-size: 11pt; line-height: 1.6; vertical-align: baseline; font-family: 돋움, dotum; letter-spacing: -0.5pt; color: rgb(0, 0, 0);">지방세포에도 직접적으로 작용할 수 있는 새로운 인슐린 저항성 약물을 개발할 수 있을 것<span style="box-sizing: border-box; margin: 0px; padding: 0px; -webkit-font-smoothing: antialiased; -webkit-print-color-adjust: exact; border: 0px; font-style: inherit; font-variant: inherit; font-weight: inherit; font-stretch: inherit; font-size: 11pt; line-height: 1.6; vertical-align: baseline; font-family: 돋움, dotum; letter-spacing: -0.5pt; color: rgb(0, 0, 0);">”<span style="box-sizing: border-box; margin: 0px; padding: 0px; -webkit-font-smoothing: antialiased; -webkit-print-color-adjust: exact; border: 0px; font-style: inherit; font-variant: inherit; font-weight: inherit; font-stretch: inherit; font-size: 11pt; line-height: 1.6; vertical-align: baseline; font-family: 돋움, dotum; letter-spacing: -0.5pt; color: rgb(0, 0, 0);">이라고 덧붙였다<span style="box-sizing: border-box; margin: 0px; padding: 0px; -webkit-font-smoothing: antialiased; -webkit-print-color-adjust: exact; border: 0px; font-style: inherit; font-variant: inherit; font-weight: inherit; font-stretch: inherit; font-size: 11pt; line-height: 1.6; vertical-align: baseline; font-family: 돋움, dotum; letter-spacing: -0.5pt; color: rgb(0, 0, 0);">.<span style="box-sizing: border-box; margin: 0px; padding: 0px; -webkit-font-smoothing: antialiased; -webkit-print-color-adjust: exact; border: 0px; font-style: inherit; font-variant: inherit; font-weight: inherit; font-stretch: inherit; font-size: 11pt; line-height: 1.6; vertical-align: baseline; font-family: 돋움, dotum; letter-spacing: -0.02em; color: rgb(0, 0, 0);">&nbsp;<div id="hwpEditorBoardContent" class="hwp_editor_board_content" data-hjsonver="1.0" data-jsonlen="22899" style="box-sizing: border-box; margin: 0px; padding: 0px; -webkit-font-smoothing: antialiased; -webkit-print-color-adjust: exact; border: 0px; font-variant-numeric: inherit; font-variant-east-asian: inherit; font-stretch: inherit; font-size: 15px; line-height: inherit; vertical-align: baseline; font-family: "Noto Sans CJK KR", "Noto Sans KR", "Noto Sans EOT", SimHei, sans-serif, 맑은고딕, "Malgun Gothic", -apple-system, BlinkMacSystemFont, "Segoe UI", Roboto, "Helvetica Neue", Arial, sans-serif, FangSong, 仿宋, STFangSong, 华文仿宋, "Apple Color Emoji", "Segoe UI Emoji", "Segoe UI Symbol", AppleGothic, Dotum, arial, sans-serif; letter-spacing: -0.3px; color: rgb(73, 73, 73); text-align: justify;" align="justify"></div><p class="0" style="box-sizing: border-box; margin-top: 20px; margin-bottom: 20px; -webkit-font-smoothing: antialiased; -webkit-print-color-adjust: exact; border: 0px; font-variant-numeric: inherit; font-variant-east-asian: inherit; font-stretch: inherit; font-size: 16px; line-height: 28.8px; vertical-align: baseline; font-family: "Noto Sans CJK KR", "Noto Sans KR", "Noto Sans EOT", SimHei, sans-serif, 맑은고딕, "Malgun Gothic", -apple-system, BlinkMacSystemFont, "Segoe UI", Roboto, "Helvetica Neue", Arial, sans-serif, FangSong, 仿宋, STFangSong, 华文仿宋, "Apple Color Emoji", "Segoe UI Emoji", "Segoe UI Symbol", AppleGothic, Dotum, arial, sans-serif; letter-spacing: -0.02em; overflow-wrap: break-word; color: rgb(102, 102, 102); text-align: justify;" align="justify"><span style="box-sizing: border-box; margin: 0px; padding: 0px; -webkit-font-smoothing: antialiased; -webkit-print-color-adjust: exact; border: 0px; font-style: inherit; font-variant: inherit; font-weight: inherit; font-stretch: inherit; font-size: 11pt; line-height: 1.6; vertical-align: baseline; font-family: 돋움, dotum; letter-spacing: -0.02em; color: rgb(0, 0, 0);">한편 이번 연구는 한국연구재단 바이오<span style="box-sizing: border-box; margin: 0px; padding: 0px; -webkit-font-smoothing: antialiased; -webkit-print-color-adjust: exact; border: 0px; font-style: inherit; font-variant: inherit; font-weight: inherit; font-stretch: inherit; font-size: 11pt; line-height: 1.6; vertical-align: baseline; font-family: 돋움, dotum; letter-spacing: 0pt; color: rgb(0, 0, 0);">·<span style="box-sizing: border-box; margin: 0px; padding: 0px; -webkit-font-smoothing: antialiased; -webkit-print-color-adjust: exact; border: 0px; font-style: inherit; font-variant: inherit; font-weight: inherit; font-stretch: inherit; font-size: 11pt; line-height: 1.6; vertical-align: baseline; font-family: 돋움, dotum; letter-spacing: -0.02em; color: rgb(0, 0, 0);">의료기술개발사업과 중견연구자지원사업의 지원을 받아 수행됐다<span style="box-sizing: border-box; margin: 0px; padding: 0px; -webkit-font-smoothing: antialiased; -webkit-print-color-adjust: exact; border: 0px; font-style: inherit; font-variant: inherit; font-weight: inherit; font-stretch: inherit; font-size: 11pt; line-height: 1.6; vertical-align: baseline; font-family: 돋움, dotum; letter-spacing: 0pt; color: rgb(0, 0, 0);">.<div style="text-align: justify;" align="justify"> </div><div style="text-align: justify;" align="justify"> </div><div style="text-align: justify;" align="justify"> </div><div style="text-align: justify;" align="justify"> </div><div style="text-align: justify;" align="justify"> </div><div style="text-align: justify;" align="justify"> </div><div style="text-align: justify;" align="justify"> </div><div style="text-align: justify;" align="justify"> </div><div style="text-align: justify;" align="justify"> </div><div style="text-align: justify;" align="justify"> </div><div style="text-align: justify;" align="justify">※ 자세한 내용은 URL을 확인하시기 바랍니다.</div>

URL : https://news.kaist.ac.kr/news/html/news/?mode=V&mng_no=16391&skey=category&sval=%EC%97%B0%EA%B5%AC&list_s_date=&list_e_date=&GotoPage=1

태그 : #건강 #만성질환 #당뇨병 #지방간 #세로토닌 #비만 #대사질환 #치료제 #사회문제 #사회문제해결 #사회문제해결플랫폼

사회문제에 대한 다양한 소식과 분석결과, 지역 사회문제 및 국내외 기관 링크를 제공합니다.

세로토닌 신호 억제를 통한 당뇨병 및 지방간 억제 효과 규명​

사회문제해결플랫폼

세로토닌 신호 억제를 통한 당뇨병 및 지방간 억제 효과 규명